The first interaction with Europeans the Pawnee had was in the 16th century. Francisco Vasquez de Coronado led Spanish explorers on an expedition. They were probably astonished to see men with hairy faces and metal armor. They took new animals brought by the Spanish. The horses enlarged the hunting area, made travel easier, and made work easier. The Europeans brought small pox, cholera, measles, tuberculosis, and many other diseases to the Pawnee Indians. This caused a great decrease in their population. Soon, Napoleon Bonaparte sold the land to the American settlers. The Pawnee began to have disagreements with the Americans.

The Spanish brought horses to the Pawnee when they came to American on explorations.
Bibliography http://college.hmco.com/history/readerscomp/naind/html/na_028300_pawnee
http://crystalinks.com/pawnee.html
http://www.olden-times.com/OldtimeNebraska/n-csnyder/nbstory/story28.html
http://www.epodunk.com/cgi-bin/politicalInfo.php?locIndex=16023
http://www.lvusd.k12.ca.us/roundsite/roundmeadow/native%20americans/pawnee.htm
http://en.wikipedia.org/wiki/Pawnee#Religion
http://en.wikipedia.org/wiki/Pawnee_language
http://www.etsu.edu/writing/amlit2000/drafts/Pawnee.htm
"Pawnee." Encyclopedia Americana. 2001
Lacey, Theresa Jense. The Pawnee. United States of America: Chelsea House Publishers, 1996.
Fradin, Dennis B. The Pawnee. Chicago: Children's Press, 1988.
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